Lp-PLA2 Activity

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an enzyme that reflects vascular inflammation and is associated with atherosclerosis. Elevated Lp-PLA2 activity levels are linked to increased risk of cardiovascular diseases, including coronary heart disease and ischemic stroke. Unlike traditional lipid markers, Lp-PLA2 specifically measures vascular-specific inflammation, making it a valuable biomarker for assessing cardiovascular risk independent of cholesterol levels. Lower activity levels are associated with reduced cardiovascular risk.