Leptin

Leptin is a hormone produced by fat cells that signals satiety (fullness) to the brain and regulates energy balance. In obesity, leptin levels are typically high, but the brain may become resistant to its signal (leptin resistance), leading to persistent hunger despite high energy stores. Measuring leptin can provide insights into body fat mass and potential leptin resistance, contributing to understanding weight regulation challenges. Lower levels within the reference range are generally better, assuming healthy body weight.