Thyroid Peroxidase Antibody (TPO)

Thyroid Peroxidase Antibodies (TPOAb) are autoantibodies targeting thyroid peroxidase, an enzyme crucial for thyroid hormone production. Like TgAb, elevated TPOAb levels are characteristic of Hashimoto's thyroiditis and are the most common indicator of thyroid autoimmunity. Their presence signifies an autoimmune attack on the thyroid gland. Ideally, levels should be negative or very low.