Thyroglobulin Antibody

Thyroglobulin Antibodies (TgAb) are autoantibodies directed against thyroglobulin, a protein produced by the thyroid gland essential for thyroid hormone synthesis. Elevated TgAb levels are a hallmark of Hashimoto's thyroiditis (autoimmune hypothyroidism) and can also be present in Graves' disease. Their presence indicates autoimmune activity against the thyroid. Ideally, levels should be negative or very low.