Thyroid
Thyroid disorders affect 20 million Americans, with women being 8 times more likely to develop thyroid problems. This comprehensive panel goes beyond basic TSH testing to evaluate complete thyroid function and autoimmunity. Essential for anyone experiencing unexplained weight changes, fatigue, hair loss, temperature sensitivity, brain fog, or mood changes. Any day, any time, no fasting — works with every donation slot.
5 tests, 5 biomarkersCategories
Overview:
Thyroid-Stimulating Hormone (TSH), produced by the pituitary gland, regulates thyroid hormone production. High TSH suggests hypothyroidism (underactive thyroid), while low TSH suggests hyperthyroidism (overactive thyroid). While standard ranges are broad (e.g., ~0.4-4.5 mIU/L), many longevity and functional medicine experts advocate for a narrower optimal range for better overall well-being, even in the absence of overt disease. Note: In elderly individuals (e.g., >70-80 years old), TSH may naturally be slightly higher (e.g., up to 5-7 mIU/L) without necessarily indicating pathology or requiring treatment.
Overview:
Free Thyroxine (Free T4) measures the unbound, biologically active form of T4, the primary hormone produced by the thyroid gland. It reflects the amount of T4 available for tissues to use or convert to the more active T3. Free T4 levels are essential for assessing thyroid status, alongside TSH and potentially Free T3.
Overview:
Free Triiodothyronine (Free T3) measures the unbound, biologically active form of T3, the most potent thyroid hormone, primarily produced by conversion from T4 in peripheral tissues. Free T3 directly influences metabolic rate and cellular function. Low levels can cause hypothyroid symptoms even if TSH and Free T4 are normal.
Overview:
Thyroid Peroxidase Antibodies (TPOAb) are autoantibodies targeting thyroid peroxidase, an enzyme crucial for thyroid hormone production. Like TgAb, elevated TPOAb levels are characteristic of Hashimoto's thyroiditis and are the most common indicator of thyroid autoimmunity. Their presence signifies an autoimmune attack on the thyroid gland. Ideally, levels should be negative or very low.
Overview:
Thyroglobulin Antibodies (TgAb) are autoantibodies directed against thyroglobulin, a protein produced by the thyroid gland essential for thyroid hormone synthesis. Elevated TgAb levels are a hallmark of Hashimoto's thyroiditis (autoimmune hypothyroidism) and can also be present in Graves' disease. Their presence indicates autoimmune activity against the thyroid. Ideally, levels should be negative or very low.
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