Ovulation Confirmation
Did I ovulate this cycle? Best taken roughly 7 days after ovulation (e.g., around day 21 of a 28-day cycle). Progesterone confirms ovulation; prolactin and TSH rule out the most common reasons it might be off. Not useful on birth control that suppresses ovulation.
3 tests, 3 biomarkersCategories
Preparation
Overview:
For males: Progesterone is a steroid hormone made in small amounts (mainly by the adrenal glands and testes). In men it’s not commonly tested, but it can be useful in specific hormone evaluations (e.g., adrenal or steroid-pathway disorders), and levels are typically low.
For females: Progesterone is a key reproductive hormone that rises after ovulation and helps prepare and support the uterine lining for pregnancy. It’s often measured to confirm ovulation, assess the luteal phase, and help evaluate irregular cycles or fertility issues.
Overview:
For males: Prolactin is a pituitary hormone. In men, elevated prolactin can suppress testosterone and contribute to low libido, erectile dysfunction, infertility, and sometimes breast symptoms. Markedly high levels should prompt evaluation for medications or a pituitary cause.
For females: Prolactin is a pituitary hormone involved in breast development and milk production. In women, elevated prolactin can cause irregular or absent periods, infertility, and sometimes breast discharge (galactorrhea). High results should be evaluated for pregnancy, medications, thyroid issues, or a pituitary cause.
Overview:
Thyroid-Stimulating Hormone (TSH), produced by the pituitary gland, regulates thyroid hormone production. High TSH suggests hypothyroidism (underactive thyroid), while low TSH suggests hyperthyroidism (overactive thyroid). While standard ranges are broad (e.g., ~0.4-4.5 mIU/L), many longevity and functional medicine experts advocate for a narrower optimal range for better overall well-being, even in the absence of overt disease. Note: In elderly individuals (e.g., >70-80 years old), TSH may naturally be slightly higher (e.g., up to 5-7 mIU/L) without necessarily indicating pathology or requiring treatment.
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