Phosphorylated tau217 (p-tau217), Plasma

Phosphorylated Tau 217 (pTau-217) is a specific form of the tau protein that becomes abnormally phosphorylated and aggregates into neurofibrillary tangles, a key hallmark of Alzheimer's disease (AD). Elevated levels of pTau-217 in blood plasma are emerging as a highly accurate and accessible biomarker for detecting AD pathology (amyloid plaques and tau tangles) even in early, preclinical stages. Assay methods and thresholds are still being standardized.